Telomerase RNA component knockout exacerbates Staphylococcus aureus pneumonia by extensive inflammation and dysfunction of T cells

Telomerase RNA component knockout exacerbates Staphylococcus aureus pneumonia by extensive inflammation and dysfunction of T cells

The telomerase RNA component (Terc) constitutes a non-coding RNA critical for telomerase function, commonly associated with aging and pivotal in immunomodulation during inflammation. Our study unveils heightened susceptibility to pneumonia caused by Staphylococcus aureus (S. aureus) in Terc knockout...

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Bibliographic Details
Main Authors: Yasmina Reisser, Franziska Hornung, Antje Häder, Thurid Lauf, Sandor Nietzsche, Bettina Löffler, Stefanie Deinhardt-Emmer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
Subjects:
Terc
Staphylococcus aureus
T cells
pneumonia
inflammation
aging
Online Access:https://elifesciences.org/articles/100433
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https://elifesciences.org/articles/100433

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