Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis

Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis

Abstract Background and aim Ulcerative colitis (UC) is characterized by complex immunological interactions involving CD4 T cell subsets and the NLRP3 inflammasome, which influence inflammatory responses. This investigation focused on delineating the activation profiles of these components and their...

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Bibliographic Details
Main Authors: Yingnan Hu, Jingyi Tang, Dian Yu, Shuo Su, Jintao Fang, Linying Xia, Wenjun Xu, Weihan Zhu, Ninping Song, Fengyong Wang, Dechang Diao, Wei Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Gastroenterology
Subjects:
Ulcerative colitis
CD4 T cell
NLRP3 inflammasome
Correlation
Diagnostic value
Online Access:https://doi.org/10.1186/s12876-025-03603-w
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