Chimeric antigen receptor NK-92 cell function is modulated by HLA class I expression of target cells

Chimeric antigen receptor NK-92 cell function is modulated by HLA class I expression of target cells

Summary: Chimeric antigen receptors – natural killer (CAR-NK) cells are a promising new cancer treatment approach. They possess distinct benefits over CAR-T cells, including an intrinsic ability to differentiate between malignant and non-malignant cells, and a lower risk of graft-versus-host disease...

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Bibliographic Details
Main Authors: Nicolai Stransky, Ranran Ji, Lukas Prause, Katrin Ganser, Winfried S. Wels, Peter Ruth, Stephan M. Huber, Franziska Eckert
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Biological sciences
Immunology
Components of the immune system
Specialized functions of cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007849
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