Craniofacial Effects of Zoledronic Acid on the Osteogenesis Imperfecta Mouse (−/−) Model of Severe Osteogenesis Imperfecta

Craniofacial Effects of Zoledronic Acid on the Osteogenesis Imperfecta Mouse (−/−) Model of Severe Osteogenesis Imperfecta

<b>Background:</b> Osteogenesis imperfecta (OI) is a rare genetic disorder affecting mainly type I collagen, which leads to bone fragility and deformities. OI patients also present craniofacial abnormalities such as macrocephaly and malocclusion. Recently, craniofacial dysmorphism was hi...

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Bibliographic Details
Main Authors: Gaspard Jeannerod, Antoine Chretien, Grégoire André, Guillaume Mabilleau, Catherine Behets
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
osteogenesis imperfecta
oim
zoledronic acid
craniofacial abnormalities
Online Access:https://www.mdpi.com/2227-9059/12/12/2692
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