How to Write a Systematic Review with Meta-analysis?
Systematic reviews (SRs) and meta-analyses are considered to be the highest level of evidence. They attempt to synthesize the existing original research and provide a structured and comprehensive approach to evaluate the existing evidence on any given research question. This article attempts to prov...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | International Journal of Advanced Medical and Health Research |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijamr.ijamr_263_24 |
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| _version_ | 1841554555249098752 |
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| author | Sandeep Grover Chandrima Naskar |
| author_facet | Sandeep Grover Chandrima Naskar |
| author_sort | Sandeep Grover |
| collection | DOAJ |
| description | Systematic reviews (SRs) and meta-analyses are considered to be the highest level of evidence. They attempt to synthesize the existing original research and provide a structured and comprehensive approach to evaluate the existing evidence on any given research question. This article attempts to provide an overview of how a SR differs from other types of reviews and provides information on how to do a SR and meta-analysis. SRs differ from other types of reviews in terms of having a well-defined research question, systematic literature search, predefined eligibility criteria and outcomes, assessment of study quality, synthesis of findings, and, if possible, a meta-analysis. The different steps involved in carrying out a SR include defining the research question (by using the PICOT framework, i.e. population, intervention, comparison, outcome, and timeframe), developing a protocol and registering the same, carrying out a comprehensive literature search, carefully selecting the studies, extracting the data, assessing the quality of the included studies, data synthesis, and interpretation of results. For meta-analysis, additional steps involve the calculation of effect sizes, choosing the appropriate model for analysis (fixed vs. random effects), preparation of forest plots, assessment of publication bias, and doing subgroup/sensitivity analyses. |
| format | Article |
| id | doaj-art-43d7cd559f2c4866a30a5949bd3ca19f |
| institution | Kabale University |
| issn | 2349-4220 2350-0298 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Advanced Medical and Health Research |
| spelling | doaj-art-43d7cd559f2c4866a30a5949bd3ca19f2025-01-08T13:21:59ZengWolters Kluwer Medknow PublicationsInternational Journal of Advanced Medical and Health Research2349-42202350-02982024-12-0111213213910.4103/ijamr.ijamr_263_24How to Write a Systematic Review with Meta-analysis?Sandeep GroverChandrima NaskarSystematic reviews (SRs) and meta-analyses are considered to be the highest level of evidence. They attempt to synthesize the existing original research and provide a structured and comprehensive approach to evaluate the existing evidence on any given research question. This article attempts to provide an overview of how a SR differs from other types of reviews and provides information on how to do a SR and meta-analysis. SRs differ from other types of reviews in terms of having a well-defined research question, systematic literature search, predefined eligibility criteria and outcomes, assessment of study quality, synthesis of findings, and, if possible, a meta-analysis. The different steps involved in carrying out a SR include defining the research question (by using the PICOT framework, i.e. population, intervention, comparison, outcome, and timeframe), developing a protocol and registering the same, carrying out a comprehensive literature search, carefully selecting the studies, extracting the data, assessing the quality of the included studies, data synthesis, and interpretation of results. For meta-analysis, additional steps involve the calculation of effect sizes, choosing the appropriate model for analysis (fixed vs. random effects), preparation of forest plots, assessment of publication bias, and doing subgroup/sensitivity analyses.https://journals.lww.com/10.4103/ijamr.ijamr_263_24meta-analysisreviewsystematic review |
| spellingShingle | Sandeep Grover Chandrima Naskar How to Write a Systematic Review with Meta-analysis? International Journal of Advanced Medical and Health Research meta-analysis review systematic review |
| title | How to Write a Systematic Review with Meta-analysis? |
| title_full | How to Write a Systematic Review with Meta-analysis? |
| title_fullStr | How to Write a Systematic Review with Meta-analysis? |
| title_full_unstemmed | How to Write a Systematic Review with Meta-analysis? |
| title_short | How to Write a Systematic Review with Meta-analysis? |
| title_sort | how to write a systematic review with meta analysis |
| topic | meta-analysis review systematic review |
| url | https://journals.lww.com/10.4103/ijamr.ijamr_263_24 |
| work_keys_str_mv | AT sandeepgrover howtowriteasystematicreviewwithmetaanalysis AT chandrimanaskar howtowriteasystematicreviewwithmetaanalysis |