Administration of trastuzumab deruxtecan in metastatic breast cancer patients with severe hepatic impairment
Background: Trastuzumab deruxtecan (T-DXd) shows efficacy in HER2-positive and HER2-low metastatic breast cancer (MBC), but its safety in patients with hepatic impairment is unclear. Methods: We report three cases of MBC patients with significant liver dysfunction treated with dose-reduced T-DXd aft...
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          | Main Authors: | Laura Sun, Gaybrielle Moore, Annalise Labatut, Jane Meisel, Kevin Kalinsky, Kristina Byers | 
|---|---|
| Format: | Article | 
| Language: | English | 
| Published: | Elsevier
    
        2024-12-01 | 
| Series: | Current Problems in Cancer: Case Reports | 
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666621924000590 | 
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