Identification of therapeutic targets for chronic kidney disease through Mendelian randomization analysis of druggable genes

Identification of therapeutic targets for chronic kidney disease through Mendelian randomization analysis of druggable genes

Abstract Chronic Kidney Disease (CKD) is a multifaceted and gradually advancing condition characterized by a complex pathogenesis. The current therapeutic options for CKD remain limited in efficacy. Consequently, the identification and exploration of novel drug targets for CKD are of paramount impor...

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Bibliographic Details
Main Authors: Run-Sen Liang, Jin-Qi Su, Xiang-Qi Wu, Qi Wang, Yong-Mei Cai, Hong-Yong Su, Ji-Xin Tang, Cui-Wei Yao
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Chronic kidney disease
TUBB
Druggable genes
Mendelian randomization analysis
Online Access:https://doi.org/10.1038/s41598-025-94761-0
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https://doi.org/10.1038/s41598-025-94761-0

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