Genome‐Wide 5‐Methylcytosine and 5‐Hydroxymethylcytosine Signatures Analysis of Plasma Cell‐Free DNA in Schizophrenia

Genome‐Wide 5‐Methylcytosine and 5‐Hydroxymethylcytosine Signatures Analysis of Plasma Cell‐Free DNA in Schizophrenia

ABSTRACT Schizophrenia (SCZ) is a highly heritable neuropsychiatric disorder that affects ∼1% of people globally. Despite extensive research, there remains a lack of biomarkers for SCZ diagnosis and disease pathogenesis delineation. Cell‐free DNA (cfDNA), which carries the genetic and epigenetic sig...

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Bibliographic Details
Main Authors: Gang Xue, Xia Wei, Li Li, Qi Zhang, Shanming Liu, Jun Zhang, Wen Hu, Qiannan Zhao, Wenjing Zhang, Chunyan Luo, Qiyong Gong, Bo Zhang, Dan Xie, Su Lui
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:MedComm
Subjects:
schizophrenia
cell‐free DNA
5‐methylcytosine
5‐hydroxymethylcytosine
magnetic resonance imaging
Online Access:https://doi.org/10.1002/mco2.70293
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https://doi.org/10.1002/mco2.70293

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