Metabolic Dysfunction-Associated Steatotic Liver Disease Is Accompanied by Increased Activities of Superoxide Dismutase, Catalase, and Carbonyl Reductase 1 and Levels of miR-200b-3p in Mouse Models

Metabolic Dysfunction-Associated Steatotic Liver Disease Is Accompanied by Increased Activities of Superoxide Dismutase, Catalase, and Carbonyl Reductase 1 and Levels of miR-200b-3p in Mouse Models

Metabolic dysfunction-associated steatotic liver disease (MASLD), one of the leading causes of chronic liver disorders, is characterized by hepatic lipid accumulation. MASLD causes alterations in the antioxidant defense system, lipid, and drug metabolism, resulting in impaired antioxidant status, he...

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Main Authors: Gabriela Svobodová, Michaela Šadibolová, Eva Velecká, Lucia Mráziková, Petra Vaculová, Petra Matoušková, Jaroslav Kuneš, Lenka Maletínská, Iva Boušová
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Antioxidants
Subjects:
metabolic dysfunction-associated steatotic liver disease (MASLD)
high fat, fructose, and cholesterol (FFC) diet
monosodium glutamate (MSG)
detoxification enzymes
miRNAs
mice
Online Access:https://www.mdpi.com/2076-3921/13/11/1371
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