Reduced GATA1 levels are associated with ineffective erythropoiesis in sickle cell anemia

Reduced GATA1 levels are associated with ineffective erythropoiesis in sickle cell anemia

Ineffective erythropoiesis (IE) is defined as the abnormal differentiation and excessive destruction of erythroblasts in the marrow, accompanied by an expanded progenitor compartment and relative reduction in the production of reticulocytes. It is a defining feature of many types of anemia, includi...

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Main Authors: Sara El Hoss, Panicos Shangaris, John Brewin, Maria Eleni Psychogyiou, Cecilia Ng, Lauren Pedler, Helen Rooks, Érica M. F. Gotardo, Lucas F. S. Gushiken, Pâmela L. Brito, Kypros H Nicolaides, Nicola Conran, David C. Rees, John Strouboulis
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11861
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https://haematologica.org/article/view/11861

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