Spatial transcriptomic analysis deciphers adipocyte-to-fibroblast transformation in bleomycin-induced murine skin fibrosis

Abstract. Background:. Scleroderma is characterized by inflammation and fibrosis, predominantly occurring in the skin and extending to various parts of the body. The pathophysiology of scleroderma is multifaceted, with the current understanding including endothelial damage, inflammatory cell infilt...

Full description

Saved in:
Bibliographic Details
Main Authors: Yixiang Zhang, Jiahao He, Fangzhou Xie, Shengzhou Shan, Jiaqi Qin, Chuandong Wang, Qingfeng Li, Yun Xie, Bin Fang, Lishao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2024-11-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000003219
Tags: Add Tag
No Tags, Be the first to tag this record!