Tailored amination enables switchable synthesis of α- and γ-amino acid derivatives from extended quinone methides

Abstract Unnatural α- and γ-amino acids display a diverse range of biological activities and serve as crucial intermediates in pharmaceutical production. Specifically, the synthesis of such molecules has been highly sought after in both academia and industry. Nevertheless, their direct synthesis fro...

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Bibliographic Details
Main Authors: Chao-Gang Zhang, Yu-Ping Tang, Qingqin Huang, Yong-Ke Qiu, Hailong Yan, Lei Dai
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60749-7
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