Tocilizumab-Based Treatment of Microvascular Inflammation in Kidney Transplant Recipients: A Retrospective Study

Tocilizumab-Based Treatment of Microvascular Inflammation in Kidney Transplant Recipients: A Retrospective Study

Chronic-active antibody mediated rejection (caAMR) is the leading causes of long-term kidney graft failure. Tocilizumab (TCZ), an anti-IL-6 receptor antibody, has been suggested as a treatment, but data are conflicting. We retrospectively studied consecutive adult kidney transplant recipients with c...

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Bibliographic Details
Main Authors: Johan Noble, Giorgia Comai, Valeria Corredetti, Reda Laamech, Celine Dard, Thomas Jouve, Diane Giovannini, Audrey Le Gouellec, Shivani Wadnerkar, Paolo Cravedi, Della Apuzzo, Daniele Vetrano, Marco Busutti, Chiara Abenavoli, Paolo Malvezzi, Lionel PE Rostaing, Gaetano Lamanna
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Transplant International
Subjects:
kidney transplantation
tocilizumab
microvascular inflammation
donor-specific antibody
chronic-active antibody-mediated rejection
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14502/full
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https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14502/full

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