D-Amino acids affect Pseudomonas aeruginosa biofilm and quorum sensing molecules in lung infection models developed under a cystic fibrosis environment

D-Amino acids affect Pseudomonas aeruginosa biofilm and quorum sensing molecules in lung infection models developed under a cystic fibrosis environment

Abstract Pseudomonas aeruginosa commonly infects immunocompromised patients, including those with cystic fibrosis (CF). These infections are difficult to treat due to a variety of factors including the ability of Pseudomonas aeruginosa to resist to antibiotic treatment in part due to formation of bi...

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Bibliographic Details
Main Authors: Joenisse M. Rosado-Rosa, Dharmeshkumar Parmar, Stanislav S. Rubakhin, Joshua D. Shrout, Jonathan V. Sweedler
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
D-Amino acids
Cystic fibrosis
Pseudomonas aeruginosa
Quorum sensing
Rhamnolipids
Biofilm
Online Access:https://doi.org/10.1038/s41598-025-10519-8
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