The genetic regulation of protein expression in cerebrospinal fluid

The genetic regulation of protein expression in cerebrospinal fluid

Abstract Studies of the genetic regulation of cerebrospinal fluid (CSF) proteins may reveal pathways for treatment of neurological diseases. 398 proteins in CSF were measured in 1,591 participants from the BioFINDER study. Protein quantitative trait loci (pQTL) were identified as associations betwee...

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Main Authors: Oskar Hansson, Atul Kumar, Shorena Janelidze, Erik Stomrud, Philip S Insel, Kaj Blennow, Henrik Zetterberg, Eric Fauman, Åsa K Hedman, Michael W Nagle, Christopher D Whelan, Denis Baird, Anders Mälarstig, Niklas Mattsson‐Carlgren
Format: Article
Language:English
Published: Springer Nature 2022-12-01
Series:EMBO Molecular Medicine
Subjects:
biomarkers
cerebrospinal fluid
genetic regulation
Mendelian randomization
pQTL
Online Access:https://doi.org/10.15252/emmm.202216359
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https://doi.org/10.15252/emmm.202216359

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