In silico prediction of the action of bromelain on PI3K/Akt signalling pathway to arrest nasopharyngeal cancer oncogenesis by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha protein

In silico prediction of the action of bromelain on PI3K/Akt signalling pathway to arrest nasopharyngeal cancer oncogenesis by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha protein

Abstract Objective This research investigates the potential anti-tumour effects of bromelain, an aqueous extract from pineapple stems and fruits, on nasopharyngeal cancer (NPC). While bromelain is known for its medicinal properties in various cancers, its impact on NPC remains unexplored. Results Us...

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Bibliographic Details
Main Authors: Alyaa Syafiqah Shamsuri, Edmund Ui -Hang Sim
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Research Notes
Subjects:
Nasopharyngeal carcinoma
Molecular docking simulation
Protein-protein interactions
Bromelain
PIK3CA
Online Access:https://doi.org/10.1186/s13104-024-06995-2
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https://doi.org/10.1186/s13104-024-06995-2

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