Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice

Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice

IntroductionAn estimated 178 million fractures occur worldwide annually, with lower limb fractures showing high rates of poor healing, often resulting in reduced mobility and chronic pain. Bone healing and the ability to bear weight are closely tied to the mechanical stability of the fracture site....

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Main Authors: Jonathan E. Layne, Dustin M. Snapper, Molly E. Czachor, Charles Lam, Jacob D. Matityahu, Dane R. G. Lind, Matthieu Huard, Johnny Huard, Kazuhito Morioka, Julian C. Motzkin, Allan I. Basbaum, Jarret A. P. Weinrich, Chelsea S. Bahney
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Physiology
Subjects:
behavioral phenotyping
fracture repair
fracture-related pain
machine-learning image analysis
sexual dimorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1630155/full
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https://www.frontiersin.org/articles/10.3389/fphys.2025.1630155/full

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