Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial
In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour chan...
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| Format: | Article |
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Frontiers Media S.A.
2025-01-01
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| Series: | Transplant International |
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| Online Access: | https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13175/full |
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| author | Regina van Zanten Monique van Dijk Joost van Rosmalen Joost van Rosmalen Denise K. Beck AnneLoes van Staa Ann Van Hecke Ann Van Hecke Emma K. Massey |
| author_facet | Regina van Zanten Monique van Dijk Joost van Rosmalen Joost van Rosmalen Denise K. Beck AnneLoes van Staa Ann Van Hecke Ann Van Hecke Emma K. Massey |
| author_sort | Regina van Zanten |
| collection | DOAJ |
| description | In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change theories and was conducted in four sessions over 6 months at the outpatient clinic. The experimental group received standard care, plus the ZENN-intervention, while the control group received only standard care. Both groups completed questionnaires at baseline, at 6 months and 1 year follow-up. At baseline, the experimental group (n = 69) scored significantly lower than the control group (n = 106) on the primary outcome Skills and Technique Acquisition (STA). No significant between-group differences were found on the secondary outcomes self-management, self-regulation, quality of life and medication adherence at T1 and T2. There was a significant increase on the self-management scale STA between T0 and T1 in the experimental group. Therefore, participants included in the experimental group had lower self-management skills at baseline and reported significant improvement after completing the intervention. No significant intervention effect was found in the primary analysis, however, for recipients with reduced self-management skills the intervention may be beneficial.Clinical Trial Registrationhttps://onderzoekmetmensen.nl/en/trial/24150, Netherlands Trial Register NL8469. |
| format | Article |
| id | doaj-art-4060c06a3c17467d9680343b2659f831 |
| institution | Kabale University |
| issn | 1432-2277 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Transplant International |
| spelling | doaj-art-4060c06a3c17467d9680343b2659f8312025-01-06T16:45:17ZengFrontiers Media S.A.Transplant International1432-22772025-01-013710.3389/ti.2024.1317513175Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled TrialRegina van Zanten0Monique van Dijk1Joost van Rosmalen2Joost van Rosmalen3Denise K. Beck4AnneLoes van Staa5Ann Van Hecke6Ann Van Hecke7Emma K. Massey8Department of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Rotterdam, NetherlandsDepartment of Internal Medicine, Section Nursing Science, Erasmus Medical Center, Rotterdam, NetherlandsDepartment of Biostatistics, Erasmus Medical Center, Rotterdam, NetherlandsDepartment of Epidemiology, Erasmus Medical Center, Rotterdam, NetherlandsDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Rotterdam, NetherlandsResearch Centre Innovations in Care, University of Applied Sciences Rotterdam, Rotterdam, NetherlandsDepartment of Public Health and Primary Care, University Centre of Nursing and Midwifery, Ghent University, Ghent, BelgiumDepartment of Nursing Director, Ghent University Hospital, Ghent, BelgiumDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Rotterdam, NetherlandsIn this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change theories and was conducted in four sessions over 6 months at the outpatient clinic. The experimental group received standard care, plus the ZENN-intervention, while the control group received only standard care. Both groups completed questionnaires at baseline, at 6 months and 1 year follow-up. At baseline, the experimental group (n = 69) scored significantly lower than the control group (n = 106) on the primary outcome Skills and Technique Acquisition (STA). No significant between-group differences were found on the secondary outcomes self-management, self-regulation, quality of life and medication adherence at T1 and T2. There was a significant increase on the self-management scale STA between T0 and T1 in the experimental group. Therefore, participants included in the experimental group had lower self-management skills at baseline and reported significant improvement after completing the intervention. No significant intervention effect was found in the primary analysis, however, for recipients with reduced self-management skills the intervention may be beneficial.Clinical Trial Registrationhttps://onderzoekmetmensen.nl/en/trial/24150, Netherlands Trial Register NL8469.https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13175/fullnurse practitionerspatient participationmotivationgoalself-efficacy |
| spellingShingle | Regina van Zanten Monique van Dijk Joost van Rosmalen Joost van Rosmalen Denise K. Beck AnneLoes van Staa Ann Van Hecke Ann Van Hecke Emma K. Massey Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial Transplant International nurse practitioners patient participation motivation goal self-efficacy |
| title | Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial |
| title_full | Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial |
| title_fullStr | Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial |
| title_full_unstemmed | Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial |
| title_short | Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial |
| title_sort | nurse led self management support after organ transplantation a multicenter stepped wedge randomized controlled trial |
| topic | nurse practitioners patient participation motivation goal self-efficacy |
| url | https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13175/full |
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