A Universal Strategy of Anti‐Tumor mRNA Vaccine by Harnessing “Off‐the‐Shelf” Immunity

A Universal Strategy of Anti‐Tumor mRNA Vaccine by Harnessing “Off‐the‐Shelf” Immunity

Abstract Personalized neoantigen cancer mRNA vaccines are promising candidates for precision medicine. However, the difficulty of identifying neoantigens heavily hinders their broad applicability. This study developed a universal strategy of anti‐tumor mRNA vaccine by harnessing “off‐the‐shelf” immu...

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Bibliographic Details
Main Authors: Jiayan Fu, Shuangqi Wu, Nengcheng Bao, Lili Wu, Huiru Qu, Zhechao Wang, Haiyang Dong, Jian Wu, Yongfeng Jin
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
anti‐tumor
mRNA vaccine
proof of concept
spontaneous cancer regression
universal strategy
Online Access:https://doi.org/10.1002/advs.202401287
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https://doi.org/10.1002/advs.202401287

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