Lipid-lowering drug and complement factor H genotyping–personalized treatment strategy for age-related macular degeneration

Lipid-lowering drug and complement factor H genotyping–personalized treatment strategy for age-related macular degeneration

Summary: We investigated whether the effect of lipid-lowering drugs (LLDs) on age-related macular degeneration (AMD) differs according to the main complement genetic variants in Singapore Epidemiology of Eye Diseases (SEED) (n = 5,579) and UK Biobank studies (n = 445,727). The effect of LLD was dete...

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Main Authors: Can Can Xue, Kelvin Y.C. Teo, Yih Chung Tham, Hengtong Li, Sahil Thakur, Charumathi Sabanayagam, Qiao Fan, David L. Silver, Xiaomeng Wang, Chui Ming Gemmy Cheung, Tien Yin Wong, Usha Chakravarthy, Ching-Yu Cheng, Simon Nusinovici
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Health sciences
Medicine
Medical specialty
Internal medicine
Cardiovascular medicine
Pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025690
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