Histopathological effects of hypervitaminosis-D and the protective role of fetuin-A in renal, hepatic, and cardiac tissues in a murine model

Histopathological effects of hypervitaminosis-D and the protective role of fetuin-A in renal, hepatic, and cardiac tissues in a murine model

Abstract Hypervitaminosis D leads to toxic effects, including hypercalcemia, which can cause severe damage to various organs. Fetuin-A, a glycoprotein with anti-inflammatory properties, may protect tissues from such damage. This study explores the role of Fetuin-A in mitigating hypervitaminosis D-in...

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Bibliographic Details
Main Authors: Maha A. Mohamed, Mohamed Hussein, Shefaa Moustafa, Yalda Rahmani, Tooba Ahmed Durrani, Shiza Ali, Hafsa Ubaid Chhapra, Elshimaa Ali, Mariam Shadan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Hypervitaminosis D
Fetuin-A
Tissue damage
Calcification
Vitamin D toxicity
Online Access:https://doi.org/10.1038/s41598-025-85200-1
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