Histone variant H2A.Z cooperates with EBNA1 to maintain Epstein-Barr virus latent epigenome

Histone variant H2A.Z cooperates with EBNA1 to maintain Epstein-Barr virus latent epigenome

ABSTRACT Chromatin structure plays a central role in the regulation of Epstein-Barr virus (EBV) latency. The histone variant H2A.Z.1 has been implicated in chromatin structures associated with the initiation of transcription and DNA replication. Here, we investigate the functional role of H2AZ.1 in...

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Main Authors: Leonardo Josué Castro-Muñoz, Davide Maestri, Leena Yoon, Bhanu Chandra Karisetty, Italo Tempera, Paul Lieberman
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
herpesviruses
epigenetic
latency
Epstein-Barr virus
histones
Online Access:https://journals.asm.org/doi/10.1128/mbio.00302-25
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https://journals.asm.org/doi/10.1128/mbio.00302-25

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