Isoimperatorin, a natural furanocoumarin, ameliorates ulcerative colitis by inducing Treg cell generation and promoting mucosal healing

Isoimperatorin, a natural furanocoumarin, ameliorates ulcerative colitis by inducing Treg cell generation and promoting mucosal healing

Abstract Background Ulcerative colitis (UC), an autoimmune disorder characterized by chronic intestinal inflammation, primarily targets the colonic mucosa. Isoimperatorin is a natural furanocoumarin compound with a variety of pharmacological activities. However, its therapeutic potential and underly...

Full description

Saved in:
Bibliographic Details
Main Authors: Yulai Fang, Shichen Min, Hongxin Chen, Zhenxing Zhu, Yanan Li, Yiheng Tong, Jingyi Hu, Lei Zhu, Hong Shen
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Molecular Medicine
Subjects:
Isoimperatorin
Ulcerative colitis
Treg cell generation
Epithelial cell migration
Mucosal healing
Online Access:https://doi.org/10.1186/s10020-025-01334-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s10020-025-01334-y

Similar Items