YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation

YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation

Abstract Psoriasis is an autoinflammatory skin disease characterized by the abnormal activation of epidermal keratinocytes. The Hippo-YAP pathway is an evolutionarily conserved pathway that plays important roles in organ size control and tumorigenesis. Recently, accumulating evidence demonstrated th...

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Main Authors: Cong Huang, Wenting Li, Changbing Shen, Bin Jiang, Kaoyuan Zhang, Xiahong Li, Weilong Zhong, Zizhuo Li, Zhenzhen Chen, Chaofeng Chen, Xingling Jian, Xiaoming Liu, Haiyan Huang, Lili Yang, Bo Yu
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07521-3
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https://doi.org/10.1038/s41419-025-07521-3

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