Rapid and sensitive liquid chromatographic–tandem mass spectrometric methods for the quantitation of dolutegravir in human plasma and breast milk

Background: Dolutegravir (DTG) is part of a first-line antiretroviral therapy (ART) for HIV management in drug-naïve individuals and is recommended for the treatment of HIV during pregnancy. Robust analytical tools to quantify DTG are necessary to support clinical trials that characterize its multi-...

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Bibliographic Details
Main Authors: Ashley R. Rackow, Aashish Pandey, Amelia L. Price, Mark A. Marzinke
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X24000300
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