Expression of TGFB3 in Pyogenic Granuloma

Objective: The aim of the study was to determine the expression of TGFB3 in pyogenic granuloma. Material and Methods: Pathologist used a double-headed light microscope to calculate cutoff values for all the antibodies employed in the investigation. Stained slides were thoroughly washed for 4 minute...

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Main Author: Asmaa Ali Hussein
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2025-08-01
Series:Dentistry 3000
Subjects:
Online Access:http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/950
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author Asmaa Ali Hussein
author_facet Asmaa Ali Hussein
author_sort Asmaa Ali Hussein
collection DOAJ
description Objective: The aim of the study was to determine the expression of TGFB3 in pyogenic granuloma. Material and Methods: Pathologist used a double-headed light microscope to calculate cutoff values for all the antibodies employed in the investigation. Stained slides were thoroughly washed for 4 minutes with Gill's Hematoxylin Solution, dehydrated, and mounted using DPX mounting solution. Results: Transforming growth factor beta-3 protein expression was measured using immunohistochemistry. In pyogenic granuloma tissues expression, negative scores (0) were found in 4.5 of 16 samples (18.1%), whereas positive values (+) were found in 10 of 16 samples (33.06%). Conclusion: TGFB3 is expressed in most pyogenic granulomas.
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issn 2167-8677
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publisher University Library System, University of Pittsburgh
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spelling doaj-art-3d4c12650f5d4d7d8c1a0e39a8b7e7992025-08-20T04:00:51ZengUniversity Library System, University of PittsburghDentistry 30002167-86772025-08-0113110.5195/d3000.2025.950Expression of TGFB3 in Pyogenic Granuloma Asmaa Ali Hussein0Ministry of Higher education and Scientific Research Al-Fallujah University College of Medicine Department of Anatomy Objective: The aim of the study was to determine the expression of TGFB3 in pyogenic granuloma. Material and Methods: Pathologist used a double-headed light microscope to calculate cutoff values for all the antibodies employed in the investigation. Stained slides were thoroughly washed for 4 minutes with Gill's Hematoxylin Solution, dehydrated, and mounted using DPX mounting solution. Results: Transforming growth factor beta-3 protein expression was measured using immunohistochemistry. In pyogenic granuloma tissues expression, negative scores (0) were found in 4.5 of 16 samples (18.1%), whereas positive values (+) were found in 10 of 16 samples (33.06%). Conclusion: TGFB3 is expressed in most pyogenic granulomas. http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/950ProteinInflammationDiagnosisTreatment
spellingShingle Asmaa Ali Hussein
Expression of TGFB3 in Pyogenic Granuloma
Dentistry 3000
Protein
Inflammation
Diagnosis
Treatment
title Expression of TGFB3 in Pyogenic Granuloma
title_full Expression of TGFB3 in Pyogenic Granuloma
title_fullStr Expression of TGFB3 in Pyogenic Granuloma
title_full_unstemmed Expression of TGFB3 in Pyogenic Granuloma
title_short Expression of TGFB3 in Pyogenic Granuloma
title_sort expression of tgfb3 in pyogenic granuloma
topic Protein
Inflammation
Diagnosis
Treatment
url http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/950
work_keys_str_mv AT asmaaalihussein expressionoftgfb3inpyogenicgranuloma