A retrospective study on beta-blocker use and outcomes in hematopoietic stem cell transplant patients

A retrospective study on beta-blocker use and outcomes in hematopoietic stem cell transplant patients

Recent studies have linked beta-blocker (BB) use in critical care settings with improved survival outcomes, potentially due to beta-adrenergic receptor (β-AR) blockade and associated anti-inflammatory effects. Given the immune system’s role in the development of graft-versus-host disease (GVHD)—a ma...

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Main Authors: Matthew A. Bergens, John T. Bokman, Ernaya J. Johnson, Matthew L. Braun, Yan Li, Amy T. Bush, Lauren Hill, Jolien Van Opstal, Alessandro Racioppi, Rebecca Fan, Sejal Kaushik, Edwin Alyea, Nelson Chao, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Richard Lopez, Sendhilnathan Ramalingam, Keith Sullivan, Paul Wischmeyer, Anthony D. Sung
Format: Article
Language:English
Published: PeerJ Inc. 2025-08-01
Series:PeerJ
Subjects:
Beta blockers
Graft-versus-host disease
Clinical outcomes
Hematopoietic stem cell transplant
Hematological malignancies
Retrospective
Online Access:https://peerj.com/articles/19822.pdf
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https://peerj.com/articles/19822.pdf

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