Prostaglandin E2 dependent migration of human brain endothelial cells is mediated through Rho-Kinase-II.

Prostaglandin E2 (PGE2), that plays a crucial role in angiogenesis as well as in ischemic and inflammatory disorders of the brain, is associated with breakdown of the blood-brain barrier (BBB). Previously, we had shown that PGE2-induced human brain endothelial cells (HBECs) migration, and works in a...

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Bibliographic Details
Main Authors: Gausal Azam Khan, Arjun Ghosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326312
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