Modulation of Nrf2 expression by targeting i-motif DNA

Abstract Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key regulator of cell detoxification, which maintains homoeostasis in healthy cells and promotes chemoresistance in cancer cells. Controlling the expression of this transcription factor is therefore of great interest. There are many co...

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Bibliographic Details
Main Authors: E. F. Warner, D. Guneri, M. A. O’Connell, C. J. MacDonald, Z. A. E. Waller
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01387-w
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