Modulation of Nrf2 expression by targeting i-motif DNA
Abstract Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key regulator of cell detoxification, which maintains homoeostasis in healthy cells and promotes chemoresistance in cancer cells. Controlling the expression of this transcription factor is therefore of great interest. There are many co...
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Main Authors: | E. F. Warner, D. Guneri, M. A. O’Connell, C. J. MacDonald, Z. A. E. Waller |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-024-01387-w |
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