Basophil activation test to BNT162b2 lacks specificity for predicting allergic reactions to the mRNA vaccine

Background: Allergic reactions to the coronavirus 2019 disease (COVID-19) mRNA vaccine (BNT162b2) were originally reported at higher rates than expected, contributing to vaccine hesitancy and, in some cases, unnecessary vaccine avoidance. Identification of a test that accurately predicts allergic re...

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Main Authors: Sydney Ann Kee, PhD, Ana Olivera, PhD, Lindsay Chatman, MSc, Muhammad B. Khalid, MD, Min Jenny Li, PhD, Eric Chu, MA, Ellen Zektser, BSN, MPH, Karen Laky, PhD, Pamela A. Frischmeyer-Guerrerio, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000967
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