Chromosome alignment and Kif18A action rely on spindle-localized control of Cdk1 activity

IntroductionDuring mitosis, chromosome alignment at the mitotic spindle equator grants correct chromosome segregation and proper nuclei formation in daughter cells. The kinesin 8 family member Kif18A plays a crucial role for chromosome alignment by localizing at the kinetochore-microtubule (K-MT) pl...

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Bibliographic Details
Main Authors: Angela Flavia Serpico, Caterina Pisauro, Asia Trano, Domenico Grieco
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1490781/full
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