Evaluation of insulin sensitivity in mice using 13C-glucose labeled clamp technique

Objective To establish a 13C isotope-labeled hyperinsulinemic-euglycemic clamp model for the assessment of insulin sensitivity in mice. Methods The mouse model of insulin resistance was established by high-fat diet feeding. The phosphorylation level of downstream insulin signaling protein, Protein...

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Bibliographic Details
Main Author: CAO Kexin, LIU Zhuohang, JIANG Yishen, SUN Xu, CHEN Jie
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-04-01
Series:Jichu yixue yu linchuang
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Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-4-442.pdf
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