Prognostic significance of CD8 and TCF1 double positive T cell subset in microsatellite unstable gastric cancer

Prognostic significance of CD8 and TCF1 double positive T cell subset in microsatellite unstable gastric cancer

Abstract Microsatellite instability-high (MSI-H) gastric cancer (GC) exhibits high tumor-infiltrating lymphocyte (TIL) density. Despite the recognized significance of the immune microenvironment in MSI-H GC, our understanding of TIL remains limited. This study aimed to investigate the clinicopatholo...

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Bibliographic Details
Main Authors: Juhyeong Park, Soo Kyung Nam, Yoonjin Kwak, Hyeon Jeong Oh, Seong-Ho Kong, Do Joong Park, Hyuk-Joon Lee, Han-Kwang Yang, Hye Seung Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Stomach neoplasms
Microsatellite instability
Tumor-Infiltrating Lymphocytes
T cell transcription factor 1
Alpha E integrins
Online Access:https://doi.org/10.1038/s41598-024-80450-x
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https://doi.org/10.1038/s41598-024-80450-x

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