Prediction of retention time in larger antisense oligonucleotide datasets using machine learning

Antisense oligonucleotides (ASOs) are nucleic acid molecules with transformative therapeutic potential, especially for diseases that are untreatable by traditional drugs. However, the production and purification of ASOs remain challenging due to the presence of unwanted impurities. One tool successf...

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Bibliographic Details
Main Authors: Manal Rahal, Bestoun S. Ahmed, Christoph A. Bauer, Johan Ulander, Jörgen Samuelsson
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Machine Learning with Applications
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666827025000933
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