Coculturing Streptomyces sp. with Acanthamoeba polyphaga enhances the antimicrobial effectiveness of its crude extract against multidrug-resistant Pseudomonas aeruginosa and Escherichia coli

Coculturing Streptomyces sp. with Acanthamoeba polyphaga enhances the antimicrobial effectiveness of its crude extract against multidrug-resistant Pseudomonas aeruginosa and Escherichia coli

Abstract Bacterial infections stand as prominent contributors to global mortality and morbidity rates. Harnessing the potential antimicrobial activity of secondary metabolites derived from natural sources holds promise for developing novel therapeutic drugs. Streptomyces spp. represents pivotal micr...

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Main Authors: KELI C.C. BARROSO, VERIDIANA G. VIRGINIO, BENI J.M. CHAÚQUE, VINICIUS J. MASCHIO, SUELI T. VAN DER SAND, MARILISE B. ROTT
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2025-04-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Acanthamoeba polyphaga
Streptomyces sp
coculture
crude extract
antimicrobial secondary metabolites
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652025000200902&lng=en&tlng=en
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