Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization

Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization

Abstract Schizophrenia (SCZ) is a complex psychiatric disorder presenting challenges for characterization. The current study aimed to identify and evaluate disease‐responsive essential genes (DREGs) to enhance the molecular characterization of SCZ. RNA‐sequencing data from PsychENCODE (536 SCZ patie...

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Main Authors: Tong Ni, Yu Sun, Zefeng Li, Tao Tan, Wei Han, Miao Li, Li Zhu, Jing Xiao, Huiying Wang, Wenpei Zhang, Yitian Ma, Biao Wang, Di Wen, Teng Chen, Justin Tubbs, Xiaofeng Zeng, Jiangwei Yan, Hongsheng Gui, Pak Sham, Fanglin Guan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
characterization
machine learning
molecular signatures
schizophrenia
transcriptome
Online Access:https://doi.org/10.1002/advs.202407628
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