M1 macrophage-membrane-cloaked paclitaxel/β-elemene nanoparticles targeting cervical cancer for enhanced therapy

M1 macrophage-membrane-cloaked paclitaxel/β-elemene nanoparticles targeting cervical cancer for enhanced therapy

Cervical cancer is a leading cause of cancer-related mortality in females worldwide, necessitating urgent solutions for effective treatment. Paclitaxel (PTX), a natural diterpene alkaloid compound, has the ability to inhibit mitosis and induce programmed apoptosis in tumor cells. However, its toxici...

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Bibliographic Details
Main Authors: Yi Wang, Jiakun Wang, Chengbo Huang, Yang Ding, Leyao Lv, Yuhao Zhu, Nuo Chen, Yingyi Zhao, Qing Yao, Shengjie Zhou, Mei Chen, Qibing Zhu, Lifeng Li, Fengyun Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Biomimetic nanoparticles
Macrophage membrane coating
β-Elemene
PTX
Cervical cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000483
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