Towards Reliable Methodology: Microbiome Analysis of Fresh Frozen vs. Formalin-Fixed Paraffin-Embedded Bladder Tissue Samples: A Feasibility Study

Towards Reliable Methodology: Microbiome Analysis of Fresh Frozen vs. Formalin-Fixed Paraffin-Embedded Bladder Tissue Samples: A Feasibility Study

Studies have shown that the human microbiome influences the response to systemic immunotherapy. However, only scarce data exist on the impact of the urinary microbiome on the response rates of bladder cancer (BC) to local <i>Bacillus Calmette-Guérin</i> instillation therapy. We launched...

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Bibliographic Details
Main Authors: Dominik Enderlin, Uwe Bieri, Jana Gadient, Yasser Morsy, Michael Scharl, Jan Hendrik Rüschoff, Lukas John Hefermehl, Anna Nikitin, Janine Langenauer, Daniel Stephan Engeler, Beat Förster, Fabian Obrecht, Jonathan Surber, Thomas Paul Scherer, Daniel Eberli, Cédric Poyet
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Microorganisms
Subjects:
fresh frozen
formalin-fixed paraffin-embedded
microbiome
bladder cancer
alpha diversity
Online Access:https://www.mdpi.com/2076-2607/12/12/2594
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