Prx1 + progenitors give rise to new articular cartilage when conditions are permissive for endogenous regeneration

Abstract It is widely acknowledged that articular cartilage lacks the ability to regenerate. However, if such regeneration were possible, which cell type would generate new tissue? The p21 −/− mouse provides an excellent platform to explore this question, hence, we conducted lineage tracing on Paire...

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Bibliographic Details
Main Authors: Christina L. Jablonski, Dora Modrcin, John Cobb, Donna-Marie McCafferty, Paul T. Salo, Roman J. Krawetz
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-025-00425-y
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