Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells

Abstract Cisplatin (CDDP) resistance has been established to significantly impact Bladder Cancer (BCa) therapy. On the other hand, the crucial regulatory involvement of SIRT7 and EZH2 in bladder cancer development is well known. Herein, the collaborative regulatory roles and underlying mechanisms of...

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Bibliographic Details
Main Authors: Yudong Cao, Shuo Wang, Jinchao Ma, Mengping Long, Xiuli Ma, Xiao Yang, Yongpeng Ji, Xingxing Tang, Jia Liu, Chen Lin, Yong Yang, Peng Du
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07321-1
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