VIM-AS1, which is regulated by CpG methylation, cooperates with IGF2BP1 to inhibit tumor aggressiveness via EPHA3 degradation in hepatocellular carcinoma

Abstract Early tumor recurrence in hepatocellular carcinoma (HCC) remains a challenging area, as the mechanisms involved are not fully understood. While microvascular invasion is linked to early recurrence, established biomarkers for diagnosis and prognostication are lacking. In this study, our obje...

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Bibliographic Details
Main Authors: Su-hyang Han, Je Yeong Ko, Sungju Jung, Sumin Oh, Do Yeon Kim, Eunseo Kang, Myung Sup Kim, Kyung-Hee Chun, Kyung Hyun Yoo, Jong Hoon Park
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01352-6
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