U-rich elements drive pervasive cryptic splicing in 3’ UTR massively parallel reporter assays
Abstract Untranslated RNA sequences play essential roles in orchestrating gene expression. However, the sequence codes and mechanisms underpinning post-transcriptional regulation remain incompletely understood. Here, we revisit the finding from a prior massively parallel reporter assay (MPRA) that A...
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| Main Authors: | Khoa Dao, Courtney F. Jungers, Sergej Djuranovic, Anthony M. Mustoe |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62000-9 |
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