Locus-specific differential expression of human satellite sequences in the nuclei of cancer cells and heat-shocked cells

Locus-specific differential expression of human satellite sequences in the nuclei of cancer cells and heat-shocked cells

Human satellites (HSats) are pericentric, tandemly repeating satellite DNA sequences in the human genome. While silent in normal cells, a subset of HSat2 noncoding RNA is expressed and accumulates in the nucleus of cancer cells. We developed a FISH-based approach for identification of the distributi...

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Main Authors: Christina Rabeler, Nicholas Paterna, Rajiv Potluri, Lia R. D’Alessandro, Anusha Bhatia, Shu Yi Chen, Johanna Lee, Bereketab Abeje, Benjamin Lipchin, Benjamin R Carone, Dawn M. Carone
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Nucleus
Subjects:
Satellite DNA
pericentromere
centromere
Cancer
repetitive DNA
heat shock
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2024.2431239
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https://www.tandfonline.com/doi/10.1080/19491034.2024.2431239

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