Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene

Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene

Background: The treatment of gastric cancer (GC) is still quite challenging. Yet, marine invertebrates have been found to produce a wide range of anticancer bioactive compounds that show promise in fighting cancer. The present study aimed to evaluate whether saponin derived from Holothuria leucospil...

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Bibliographic Details
Main Authors:	Khadijeh Sadegh, Amirhossein Ahmadi, Ahmad Shadi, Ahmad Ghasemi
Format:	Article
Language:	English
Published:	Shiraz University of Medical Sciences 2025-01-01
Series:	Middle East Journal of Cancer
Subjects:	stomach neoplasms sea cucumber cadherins computational biology
Online Access:	https://mejc.sums.ac.ir/article_50008_589414eac0efe8894747bf1c3715750d.pdf
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