Promising immunotherapy targets: TIM3, LAG3, and TIGIT joined the party

Immune checkpoint inhibitors (ICIs) have shown great promise as immunotherapy for restoring T cell function and reactivating anti-tumor immunity. The US Food and Drug Administration (FDA) approved the first immune checkpoint inhibitor, ipilimumab, in 2011 for advanced melanoma patients, leading to s...

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Bibliographic Details
Main Authors: Chenyu Lu, Yuanyan Tan
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Therapy: Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924000158
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