In silico development of a multi-epitope-based vaccine against Burkholderia cepacia complex using reverse vaccinology

In silico development of a multi-epitope-based vaccine against Burkholderia cepacia complex using reverse vaccinology

BackgroundMultidrug-resistant Burkholderia cenocepacia and Burkholderia multivorans have emerged as significant pathogens, particularly in patients with cystic fibrosis (CF) and chronic granulomatous disease (CGD).ObjectiveGiven the absence of approved vaccines, this study aimed to identify potentia...

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Bibliographic Details
Main Authors: Donya Ghorbani, Masoumeh Beig, Narjes Noori Goodarzi, Mohammad Sholeh, Behzad Shahbazi, Yaser Moghaddam, Farzad Badmasti
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Virology
Subjects:
Bcc
reverse vaccinology
in silico
multi-epitope vaccine
toll-like receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2025.1520109/full
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