SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation

SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation

Abstract Sodium-glucose cotransporter 2 (SGLT-2) inhibitors have been increasingly recognized for their potential neuroprotective properties. Nevertheless, their effects on intracerebral hemorrhage (ICH) are still debated, with the precise mechanisms involved remaining unclear. Recent studies indica...

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Bibliographic Details
Main Authors: Mingsheng Huang, Yiheng Liu, Cheng Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Intracerebral hemorrhage
SGLT-2 inhibitors
Inflammatory biomarkers
Mendelian randomization
Causal effect
Online Access:https://doi.org/10.1038/s41598-024-84118-4
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https://doi.org/10.1038/s41598-024-84118-4

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