Oxygen Sensitivity of Reporter Genes: Implications for Preclinical Imaging of Tumor Hypoxia
Reporter gene techniques have been applied toward studying the physiologic phenomena associated with tumor hypoxia, a negative prognostic indicator. The purpose of this study was to assess the potential adverse effects of hypoxic conditions on the effectiveness of four commonly used reporter genes:...
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Main Authors: | Ivana Cecic, Denise A. Chan, Patrick D. Sutphin, Pritha Ray, Sanjiv Sam Gambhir, Amato J. Giaccia, Edward E. Graves |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2007-07-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2007.00017 |
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