Assessment of tuberculosis drug efficacy using preclinical animal models and in vitro predictive techniques

Abstract Tuberculosis (TB) killed approximately 1.3 million people in 2022 and remains a leading cause of death from the bacteria Mycobacterium tuberculosis (M.tb); this number of deaths was surpassed only by COVID-19, caused by the SARS-CoV-2 virus. The alarming emergence of multidrug-resistant (MD...

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Bibliographic Details
Main Authors: Hazem F. M. Abdelaal, Bryan J. Berube, Brendan K. Podell, Matthew H. Harband, Hadley E. Gary, Martin Perez-Jaimes, David F. Ackart, Valerie A. Reese, Sasha E. Larsen, Tiffany Pecor, David Z. Wilkins, Tanya Parish, Sara E. Maloney-Norcross, Jeffrey B. Mecham, Anthony J. Hickey, Susan L. Baldwin, Rhea N. Coler
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-024-00066-z
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